Magali Richard

Magali Richard

I am a CNRS researcher in bioinformatics, with a background in molecular biology, genetics, and computational biology. My research focuses on tumor heterogeneity, method development, and cancer biology, and I also promote collaborative science by organizing data challenges.

Inferring cellular heterogeneity with mixture models for DNA methylation rates

This study proposes a cell deconvolution framework based on mixtures of non-negative Beta regression models that captures latent heterogeneity in DNA methylation profiles and significantly improves cell proportion estimation compared with standard deconvolution approaches.

Recommended citation: Hugo Barbot, Yuna Blum, Magali Richard, David Causeur. Inferring cellular heterogeneity with mixture models for DNA methylation rates 2026.
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