Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach
Herein, we developed a panel of antibodies that could easily be used by researchers and pathologists. The purpose of this panel was to classify patients according to the two main subtypes of PDAC, roughly basal-like or classical. To achieve this, we selected markers through a stringent and multistep process.
Recommended citation: Hilmi M, Delecourt F, Raffenne J, Bourega T, Dusetti N, Iovanna J, Blum Y, Richard M, Neuzillet C, Couvelard A, Tihy M, de Mestier L, Rebours V, Nicolle R, Cros J. Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach. J Pathol. 2025 Apr;265(4):448-461. doi: 10.1002/path.6398. Epub 2025 Feb 11. PMID: 39935174; PMCID: PMC11880971.
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